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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22336 | Galloflavin | Dehydrogenase | |
Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent. | |||
T7200 | TAK-960 | PLK | |
TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively. | |||
T11337 | Fumarate hydratase-IN-1 | Others | |
Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM. Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor. | |||
T21804 | GW 610 | Others | |
GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0.... | |||
T15168 | DRF-1042 | Others | |
DRF-1042 acts to inhibit DNA topoisomerase I. DRF-1042 displays perfect anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype. | |||
T11823 | LB-60-OF61 | NAMPT | |
LB-60-OF61 is a NAMPT inhibitor, a NAMPT inhibitor that displays antiproliferative activity against MYC oncogene-dependent cancer cell lines. | |||
T4400 | DIM-C-pPhOH | CDIM8 | Apoptosis , Others |
DIM-C-pPhOH (CDIM8) is a nur77 (NR4A1) antagonist,inhibits TGF-β induced cell migration of breast cancer cell lines,promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines,mimi... | |||
T7293 | EC330 | Others | |
EC330, a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range. | |||
T7082 | HDAC8-IN-1 | HDAC | |
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits ... | |||
TP1427L | ReACp53 acetate | p53 | |
ReACp53 acetate could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines. | |||
T27579 | ICL-CCIC-0019 | ICL CCIC 0019 | AChR |
ICL-CCIC-0019 is an inhibitor of choline kinase alpha (ChoKα). ICL-CCIC-0019 induces G1 arrest, endoplasmic reticulum stress, and apoptosis of cancer cell lines. | |||
T24706 | RBC10 | RBC 10,RBC-10 | GTPase |
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines. | |||
T73494 | TNG908 | ||
TNG908, a MTAP-cooperative PRMT5 inhibitor capable of penetrating the blood-brain barrier, demonstrates 15-fold greater selectivity for MTAP cell lines over MTAP WT (wild type) cell lines. Its application is primarily in... | |||
TN1817 | Kaempferol 3,7,4'-trimethyl ether | Kaempferol 3,7,4'-trimethylether | NO Synthase |
Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) shows selective cyctoxic activities against the nine tested cancer cell lines. | |||
T17195 | UC-112 | Others | |
UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM). | |||
T7311 | Oxyphenisatin acetate | Autophagy | |
Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468. | |||
T5744 | 7-Prenyloxycoumarin | Nsc267697,7-O-Prenylumbelliferone | Antifungal |
7-Prenyloxycoumarin (Nsc267697) is a natural product from Heracleum dissectum,and possess preventive and therapeutic effects on breast cancer but they have also cytotoxic effects on some other cancer cell lines. | |||
T4519 | Alisol A | Alisol-A | Autophagy |
Alisol A (Alisol-A) may be an autophagic inducer, it has anti-cancer activity, it presents inhibitory effects on cancer cell lines tested(HepG2, MDA-MB-231, and MCF-7 cells). | |||
T31020 | CP 461 | OSI 461,UNII-68OJX9I7DT,CP-461,CP461 | Apoptosis , PDE |
CP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor ce... | |||
T2S0029 | 4'-Demethylpodophyllotoxin | Others | |
4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines. |